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Brimonidine (Alphagan P) is an alpha-2 agonist eye drop that lowers the amount of fluid in the eye. Generic Name(S): brimonidine View Free Coupon Uses Side Effects Precautions Interactions Overdose Images Reviews (38) Uses This medicationis used to treat open-angle glaucomaor high fluid pressure. 5 eye drops contain the active ingredient brimonidine tartrate and the preservative sodium chlorite (as purite) Drug Name : Brimonidine Brimonidine generic Alphagan-P (0. The milder, over-the-counter version only lowers the amount fluid in the blood vessels around the eye, reducing eye redness. They lower the pressure in the eye by decreasing the fluid produced and helping the flow of fluid out of the eye chamber. Brimonidine Brimonidine is a medication used to treat open-angle glaucoma, ocular hypertension, and rosacea. Bicarbonate is required for the production of the aqueous humour. 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